Histopathologic Findings in the Areas of Orange Pigment Overlying Choroidal Melanomas

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Histopathologic Findings in the Areas of Orange Pigment Overlying Choroidal Melanomas.

PURPOSE Orange pigment is an important sign of malignancy in melanocytic tumors. There is a question as to whether the pigment accumulation is inside of macrophages or retinal pigment epithelial (RPE) cells. We investigated which cells are involved with this color alteration. METHODS We examined enucleated specimens from two patients with choroidal melanoma and dense orange pigment on fundus ...

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The Development of Orange Pigment Overlying Choroidal Metastasis.

AIMS The aim of this study was to correlate the ophthalmoscopic and histopathological findings of orange pigment overlying a choroidal metastasis. METHODS This is a single case report with clinical follow-up and histopathological examination. RESULTS Histopathology revealed a choroidal metastasis with subretinal CD68-positive macrophages showing autofluorescent deposits in fluorescence micr...

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Histopathological findings in human choroidal melanomas after transpupillary thermotherapy.

AIMS The effect of transpupillary thermotherapy (TTT) on human choroidal melanomas was investigated by means of histopathology. METHODS Before enucleation TTT was performed in 11 eyes with a xenon are photocoagulator with a red filter or a diode laser at 810 nm. The exposure time was 1 minute; the estimated temperature at the top of the tumour was about 65 degrees C. RESULTS Seven of 11 tum...

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Unusual Orange-Colored Choroidal Metastases

PURPOSE To report the clinical and paraclinical features of two patients with orange- colored choroidal metastases in whom the primary cancers have not previously been associated with such lesions. CASE REPORT Orange-colored choroidal lesions were detected on the fundus examination of one patient with metastatic small cell neuroendocrine tumor of the larynx and oropharynx, and in another subj...

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ژورنال

عنوان ژورنال: Translational Vision Science & Technology

سال: 2016

ISSN: 2164-2591

DOI: 10.1167/tvst.5.3.4